Sodium borohydride → HCID 19102590, compound

HRID 1198567Notes

Reaction equation

HRID 1198567 reaction equation
[BH4-].[Na+].[C:3]1([CH:9]([N:28]2[C:36]3[C:31](=[CH:32][CH:33]=[C:34]([CH:37]=[O:38])[CH:35]=3)[CH:30]=[CH:29]2)[C:10]2[CH:15]=[CH:14][CH:13]=[C:12](/[CH:16]=[CH:17]/[C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)[CH:11]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>CO>[C:3]1([CH:9]([N:28]2[C:36]3[C:31](=[CH:32][CH:33]=[C:34]([CH2:37][OH:38])[CH:35]=3)[CH:30]=[CH:29]2)[C:10]2[CH:15]=[CH:14][CH:13]=[C:12](/[CH:16]=[CH:17]/[C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)[CH:11]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 19102579HCID 19102579, compound

Product 1

HCID 19102590HCID 19102590, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Solid sodium borohydride (0.11 g, 2.89 mmol) was added to a stirred suspension of 1-[α-phenyl-3-{2(E)-(quinolin-2-yl)ethenyl}benzyl]indole-6-carboxaldehyde (0.32 g, 0.69 mmol) in methanol (10 ml) and the mixture was stirred for 30 minutes giving a clear solution which was poured onto ammonium chloride solution and extracted with dichloromethane. The extract was dried and evaporated to give a solid product.

Workup

  1. customgiving a clear solution which
  2. additionwas poured onto ammonium chloride solution
  3. extractionextracted with dichloromethane
  4. customThe extract was dried
  5. customevaporated
  6. customto give a solid product

Sources & evidence

ORD record
ord-d8580186d5a745769d4cbb9236998ebd
Source dataset
uspto-grants-1994_01
Patent number
US05281593

Reaction notes

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