Sodium Hydroxide → HCID 19102872, compound

Participants

Reaction Steps

An aliquot of the methyl ester from Step (n) (200 mg) was hydrolyzed by stirring it in a mixture of 5 ml of 10° sodium hydroxide and 5 ml ethanol for 4 hr at 25° C. and 1 hr at 100° C. The azeotrope was distilled off, water (10 ml) was added and the resulting solution slowly acidified to pH 2.5 with 2N HCl. The resulting precipitated acid was isolated (60 mg).

Provenance & Evidence