m-Chloroperbenzoic acid → HCID 19757849, compound

HRID 1198893Notes

Reaction equation

HRID 1198893 reaction equation
[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].ClC1C=CC=C(C(OO)=[O:23])C=1>C(Cl)Cl>[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N+:11]([O-:23])[CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 10867660Diethyl pyridin-3-ylphosphonate

Product 1

HCID 19757849HCID 19757849, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1.5 g of 3-diethylphosphonopyridine, Bull. Chem. Soc. Jap. 55, 909 (1982), in 20 ml of methylene chloride is treated with 2.33 g m-chloroperbenzoic acid at room temperature. The reaction mixture is allowed to stir at room temperature overnight, then concentrated under vacuum. The residue is partitioned between ether and water, the aqueous layer is concentrated under vacuum to afford 3-(diethylphosphono)-pyridine-N-oxide as a yellow oil.

Workup

  1. concentrationconcentrated under vacuum
  2. customThe residue is partitioned between ether and water
  3. concentrationthe aqueous layer is concentrated under vacuum

Sources & evidence

ORD record
ord-cab3bff722af47a887b8ed18a3b3add8
Source dataset
uspto-grants-1990_02
Patent number
US04898854

Reaction notes

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