Methane → HCID 19867712, compound

HRID 1198940Notes

Reaction equation

HRID 1198940 reaction equation
[CH3:1][CH:2]1[C:11]2[C:6](=[C:7]([CH3:22])[CH:8]=[C:9]([NH:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[N+:19]([O-])=O)[CH:10]=2)[NH:5][C:4](=[O:23])[CH2:3]1.[H][H].C>>[CH3:1][CH:2]1[C:11]2[C:6](=[C:7]([CH3:22])[CH:8]=[C:9]([NH:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[NH2:19])[CH:10]=2)[NH:5][C:4](=[O:23])[CH2:3]1

Participants

4

Reactant 3

HCID 297MethaneHCID 19867721HCID 19867721, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19867712HCID 19867712, compound

Procedure

This compound, m.p. 195°-199°, was prepared similarly to Preparation 17 using 3,4-dihydro-4,8-dimethyl-6-[(N-2-nitrophenyl)-amino]-2-(1H)-quinolone, hydrogen and palladised charcoal as starting materials. The product was characterised spectroscopically and used directly in Examples 13, 15 and 16 without further purification.

Workup

  1. customused directly in Examples 13, 15 and 16 without further purification

Sources & evidence

ORD record
ord-8e0a0dec53584397967d79556d3e4fe7
Source dataset
uspto-grants-1990_02
Patent number
US04898872

Reaction notes

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