反应详情

To a suspension of 2-(4-nitrophthalimido)acetic acid (58.6 g) in toluene (250 ml) was added phosphorus pentachloride (48.8 g) and the mixture was refluxed for 3 hours. After completion of the reaction, the solvent was removed under reduced pressure. By addition of hexane to the residue, the title compound (62.3 g) was obtained as light yellow sharp-pointed needles.

1. temperaturethe mixture was refluxed for 3 hours
2. customAfter completion of the reaction
3. customthe solvent was removed under reduced pressure
4. additionBy addition of hexane to the residue