1-Phenylpiperazine → HCID 19867815, compound

HRID 1199031Notes

Reaction equation

HRID 1199031 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:17][C:18]([OH:20])=O)[C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2.[C:21]1([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:17][C:18](=[O:20])[N:30]2[CH2:31][CH2:32][N:27]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH2:28][CH2:29]2)[C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2

Participants

3

Reactant 2

HCID 70961-PhenylpiperazineHCID 14835398HCID 14835398, compound

Product 1

HCID 19867815HCID 19867815, compound

Procedure

The title compound is prepared by reacting the acid chloride of 5-chloro-3-phenyl-2,1-benzisoxazole-7-acetic acid with N-phenyl-piperazine in an aprotic solvent and washing the reaction mixture with sodium bicarbonate solution.

Workup

  1. washwashing the reaction mixture with sodium bicarbonate solution

Sources & evidence

ORD record
ord-e1973313e8274ddf98671e0fb8dbb04e
Source dataset
uspto-grants-1990_02
Patent number
US04898874

Reaction notes

Loading…