HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 14835404, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4,5-Diphenyl-1-(ethoxycarbonylmethyl)-pyrazole | HCID 14699551 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 14835404 | HCID 14835404 | 93.4% |
Reaction Steps
Twelve grams (0.04 mol) of ethyl 4,5-diphenyl-1-H-pyrazole-1-acetate of example 1 was refluxed in 40 mL of water, 40 mL of ethanol and 5 mL of 35% aqueous sodium hydroxide for 1.5 hours. The ethanol was stripped off, water was added, and the slurry was acidified with excess 6N HCl. The resulting precipitate was filtered off and rinsed with water to yield 10.4 g of free acid, mp 169°-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898880 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-9cbfd467f70f4b33a654aaae1db07157 |
| Source note | uspto-grants-1990_02 |