4-(3-Methoxyphenyl)but-3-en-2-one → 4-(3-Methoxyphenyl)butan-2-one

HRID 1199078Notes

Reaction equation

HRID 1199078 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11](=[O:13])[CH3:12])[CH:6]=[CH:7][CH:8]=1>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][C:11](=[O:13])[CH3:12])[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 1

HCID 1820074-(3-Methoxyphenyl)but-3-en-2-one

Product 1

HCID 114239024-(3-Methoxyphenyl)butan-2-oneYield 99.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 30.1 g of 4-(3-methoxyphenyl)-3-buten-2-one in 200 ml of MeOH was hydrogenated over 200 mg of 10% palladium on carbon for two hours. The catalyst was filtered and the solvent evaporated in vacuo to give 30.2 g of yellow oily 4-(3-methoxyphenyl)-2-butanone.

Workup

  1. filtrationThe catalyst was filtered
  2. customthe solvent evaporated in vacuo

Sources & evidence

ORD record
ord-61ca01d144964a2e98ce71468bfe29b1
Source dataset
uspto-grants-1990_02
Patent number
US04898889

Reaction notes

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