HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Cefadroxil monohydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 14996560 | HCID 14996560 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | Cefadroxil monohydrate | HCID 47964 | — |
Reaction Steps
Cefadroxil dimethylacetamide solvate (40 g) prepared according to example 1 was slurried in isopropyl alcohol (200 ml) containing 13% of water at 50° C. for 90'. The mixture was cooled to +5° C. and cefadroxil monohydrate was collected to yield 28.5 exhibiting the same X-ray diffraction pattern of an authentic sample of crystalline cefadroxil monohydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04898938 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-9ee67626a1be42f097c050d44f48f4c8 |
| Source note | uspto-grants-1990_02 |