Tetrahydrofuran → tert-butyl N-[1-hydroxy-3-[2-(trifluoromethyl)phenyl]propan-2-yl]carbamate
Reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]1[c:12]([C:17]([F:18])([F:19])[F:20])[cH:13][cH:14][cH:15][cH:16]1)[C:21](=[O:22])[OH:23]>>[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]1[c:12]([C:17]([F:18])([F:19])[F:20])[cH:13][cH:14][cH:15][cH:16]1)[CH2:21][OH:22]Participants
3
Sources & evidence
- ORD record
- ord-17c6e1cd66aa469ba19c7986c3c4d2f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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