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HRID1199134

反应详情

EQUATION

反应方程式

HRID 1199134 的结构方程式

REACTANTS

反应物

3
结构：O=C1CSC(=O)N1
HCID5437

Thiazolidinedione

C3H3NO2S

结构：C1CCNCC1
HCID8082

Piperidine

C5H11N

结构：CCc1ccc(CCOc2ccc(C=O)cc2)nc1
HCID9881522

4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzaldehyde

C16H17NO2

PRODUCTS

生成物

1
结构：CCc1ccc(CCOC(=C2SC(=O)NC2=O)c2ccccc2)nc1
HCID54391130

未命名化合物

收率 64%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A mixture of 4-[2-(5-ethyl-2-pyridyl)ethoxy]benzaldehyde (2.40 g), 2,4-thiazolidinedione (1.66 g), ethanol (40 ml) and piperidine (0.2 ml) was heated under reflux for 8 hours. The resulting crystals were recrystallized form ethyl acetate to give 2.14 g (64%) of 5-{[2-(5-ethyl-2-pyridyl)ethoxy]benzylidene}-2,4-thiazolidinedione as colorles crystals. m.p.: 165.5°-167° C.

WORKUP

后处理

  1. temperaturewas heated
  2. temperatureunder reflux for 8 hours
  3. customThe resulting crystals were recrystallized form ethyl acetate