Ammonia → HCID 178424370, compound

HRID 1199238Notes

Reaction equation

HRID 1199238 reaction equation
[C:1]1([CH3:18])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8](=S)[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH3:16].[NH3:19].O=O>O.CC([O-])=O.CC([O-])=O.[Cu+2]>[CH3:18][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][C:8]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH3:16])=[NH:19]

Participants

6

Reactant 3

HCID 222AmmoniaHCID 977Oxygen2×HCID 6880281,3-Bis(o-tolyl)thiourea

Product 1

HCID 178424370HCID 178424370, compoundYield 93.2%

Reagents, catalysts & solvents 2

HCID 8895Cupric acetateCatalystHCID 962WaterSolvent

Procedure

0.1 mol of di-o-tolylthiourea, 3 mol of ammonia, and 0.1 mmol of Cu(OAc)2 are reacted in 130 g water with oxygen. The reaction temperature is 80° C. and the oxygen pressure 3 bar. Di-o-tolylguanidine is obtained in 93.2% yield after a reaction time of 3 hours.

Workup

  1. customis 80° C.

Sources & evidence

ORD record
ord-948f02844cf24bc8828c5024b53132cc
Source dataset
uspto-grants-1990_02
Patent number
US04898978

Reaction notes

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