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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1199281Generated: November 1, 2026

Ethyl trifluoroacetate → N-butan-2-yl-2,2,2-trifluoroacetamide

https://huagongshe.com/reaction/1199281

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl trifluoroacetateHCID 9794—
ReactantSec-ButylamineHCID 24874—
ProductN-butan-2-yl-2,2,2-trifluoroacetamideHCID 587638—

Reaction Steps

In a procedure similar to Example 6, ethyl trifluoroacetate (295 g, 2.07 m) was reacted with sec-butylamine. The resulting amide distilled at 72.5° C./8 mm Hg and amounted to 285 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04899249
Source datasetuspto-grants-1990_02
ORD IDord-bfd0e5b4fecb4b57ba407bd2eba9b164
Source noteuspto-grants-1990_02