HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 2-[2-(6,7-Dimethoxy-1-isoquinolinyl)phenylsulphinyl]-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 2-[2-(6,7-Dimethoxy-1-isoquinolinyl)phenylthio]-1H-benzimidazole | HCID 19866631 | — |
| Solvent | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Chloroform dichloromethane | HCID 18399249 | — |
| Product | 2-[2-(6,7-Dimethoxy-1-isoquinolinyl)phenylsulphinyl]-1H-benzimidazole | HCID 15059540 | — |
Reaction Steps
The product of step (f) above was dissolved in 1:1 CH2Cl2 -CHCl3 (10 ml), treated with 85%m-Chloroperbenzoic acid (24 mg) at -5°, and worked up in aqueous NaHCO3 to give the title compound. NMR (CDCl3)d, 8.5 (d,1H), 8.35 (dd,1H), 7.26 (1H,s), 7.21 (1H,s), 7.7-7.2 (complex,8H), 4.30 (s,3H), 3.85 (s,3H)ppm, mp 250° (d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04900751 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-6a337853a57b44b2948d9c56aa4860ed |
| Source note | uspto-grants-1990_02 |