HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Dimethylaminopurine → 9-(2-Chloro-6-fluorobenzyl)-6-dimethylaminopurine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Dimethylaminopurine | HCID 3134 | — |
| Reactant | 1-Chloro-2-(chloromethyl)-3-fluorobenzene | HCID 108675 | — |
| Product | 9-(2-Chloro-6-fluorobenzyl)-6-dimethylaminopurine | HCID 129802 | — |
Reaction Steps
Employing N6,N6 -dimethyladenine prepared in Example 17 and 2-chloro-6-fluorobenzyl chloride, the same procedures as in Example 39, (1) were repeated to give a crude 9-(2-chloro-6-fluorobenzyl)-N6, N6 -dimethyladenine, in which the purity was 73.1% by weight and the content of the 3-isomer was 26.9% by weight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04900826 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-5b23e40cd1504488ac1410604cad6303 |
| Source note | uspto-grants-1990_02 |