HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic acid dihydrate → 4-Methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic acid dihydrate | HCID 61373 | — |
| Reactant | 2-N-methylpyridine-2,3-diamine | HCID 12343669 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-Methyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione | HCID 13192942 | — |
Reaction Steps
3-amino-2-(N-methylamino)-pyridine (0.1 mol) and oxalic acid dihydrate (0,12 mol) was dissolved in 4N HCl (400 ml). The solution was refluxed for 8 hours and then cooled to room temperature whereby the title compound precipitated as crystals. The crystals were separated by filtration and then washed with water. m.p. 271°-272° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04902686 |
| Source dataset | uspto-grants-1990_02 |
| ORD ID | ord-10f3312d2eb84e8bb731121522f952e7 |
| Source note | uspto-grants-1990_02 |