反应详情

To 11.3 ml of acetic anhydride were added 29.0 g of 3-nitrobenzaldehyde and 27.1 g of 4-isopropyl-2-methylthiazole and the reaction was carried out under nitrogen gas stream at 170° C. for 23 hours. After completion of the reaction, low boiling materials were evaporated under reduced pressure and the residue was recrystallized from ethyl ether-n-hexane to give 16.8 g (yield 32%) of the title compound as yellowish white crystals.

1. customat 170° C.
2. customfor 23 hours
3. customAfter completion of the reaction, low boiling materials
4. customwere evaporated under reduced pressure
5. customthe residue was recrystallized from ethyl ether-n-hexane