反应详情

To 30 ml of acetone were added 200 mg of 2-(trans-3-hydroxystyryl)benzothiazole, 0.11 ml of ethyl bromoacetate and 131 mg of potassium carbonate, and the mixture was refluxed for 4 hours. After cooled to room temperature, the mixture was extracted with ethyl ether, dried over anhydrous magnesium sulfate and then the solvent was evaporated under reduced pressure. After the crude crystals of the residue were washed with ethyl ether and n-hexane, they were dried under reduced pressure to give 207 ml (yield 77%) of the title compound.

1. temperaturethe mixture was refluxed for 4 hours
2. extractionthe mixture was extracted with ethyl ether
3. dry with materialdried over anhydrous magnesium sulfate
4. customthe solvent was evaporated under reduced pressure
5. washAfter the crude crystals of the residue were washed with ethyl ether and n-hexane, they
6. customwere dried under reduced pressure