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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1199789Generated: October 31, 2026

Propionic anhydride → HCID 70359626, compound

https://huagongshe.com/reaction/1199789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionic anhydrideHCID 31263—
Reactantalpha-HydroxyalprazolamHCID 162244—
SolventWaterHCID 962—
ProductHCID 70359626HCID 70359626—

Reaction Steps

In a manner similar to Example 12, a mixture of 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine and propionic anhydride was heated on the water bath to give 8-chloro-1-(hydroxymethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine propionate (ester).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04902794
Source datasetuspto-grants-1990_02
ORD IDord-4549eff1c22b495eb3630253fc39fd2e
Source noteuspto-grants-1990_02