Styrene Oxide → HCID 54200922, compound

HRID 1199925Notes

Reaction equation

HRID 1199925 reaction equation
[Br:1][C:2]1[C:3]([CH2:7][CH2:8][NH2:9])=[CH:4][S:5][CH:6]=1.[CH2:10]1[O:18][CH:11]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[OH:18][CH:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:10][NH:9][CH2:8][CH2:7][C:3]1[C:2]([Br:1])=[CH:6][S:5][CH:4]=1

Participants

3

Reactant 2

HCID 7276Styrene OxideHCID 198642934-Bromo-3-thiopheneethanamine

Product 1

HCID 54200922HCID 54200922, compound

Procedure

N-(2-hydroxy-2-phenylethyl) 4-bromo-thiophene-3-ethylamine was prepared from 4-bromothiophene-3-ethylamine and styrene oxide by the method described in Example 1(b) and recrystallised from cyclohexane (m.p. 75°).

Workup

  1. customrecrystallised from cyclohexane (m.p. 75°)

Sources & evidence

ORD record
ord-5e850c23d50a4f62a5092d1f39ccceb0
Source dataset
uspto-grants-1990_02
Patent number
US04904653

Reaction notes

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