HCID 19864513, compound → HCID 19864521, compound

Participants

Reaction Steps

4-(4-Hyrdoxybutylamino)-3-nitropyridine (6 g) was dissolved in ethanol (60 cm3) containing Raney Ni catalyst (0.5 g) and then hydrogenated at room temperature for 3 hours under pressure (30 p.s.i.=206.8 kPa). The mixture was filtered under nitrogen and the filtrate was evaporated under vacuum to yield the crude product (5.5 g) which was used directly in the next step.

Provenance & Evidence