Hydrochloric Acid → HCID 14699187, compound

HRID 1200133Notes

Reaction equation

HRID 1200133 reaction equation
[OH-].[Na+].C[O:4][C:5](=[O:36])[CH2:6][CH:7]([OH:35])[CH2:8][CH:9]([OH:34])/[CH:10]=[CH:11]/[C:12]1[C:16]2([CH2:20][CH2:19][CH2:18][CH2:17]2)[C:15]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:14][C:13]=1[C:27]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=1.Cl>C(O)C>[F:33][C:30]1[CH:29]=[CH:28][C:27]([C:13]2[CH:14]=[C:15]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:16]3([CH2:20][CH2:19][CH2:18][CH2:17]3)[C:12]=2/[CH:11]=[CH:10]/[CH:9]([OH:34])[CH2:8][CH:7]([OH:35])[CH2:6][C:5]([OH:36])=[O:4])=[CH:32][CH:31]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 14699184HCID 14699184, compound

Product 1

HCID 14699187HCID 14699187, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Aqueous 1N NaOH (13.4 ml, 13.4 mmoles) was added to a 0.2M ethanol solution of the 3,5-dihydroxy ester prepared in Step 7 (4.1 g, 8.9 mmoles). After stirring for 10 minutes, the ethanol was evaporated in vacuo. The residue was redissolved in H2O and the aqueous layer was acidified with 1N HCl (15 ml, 15 mmoles).

Workup

  1. customthe ethanol was evaporated in vacuo
  2. dissolutionThe residue was redissolved in H2O

Sources & evidence

ORD record
ord-bb6b81bdf4224ab48f553b27c2a9a497
Source dataset
uspto-grants-1990_02
Patent number
US04904691

Reaction notes

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