Hydrogen Bromide → HCID 54558383, compound

HRID 1200279Notes

Reaction equation

HRID 1200279 reaction equation
[PH:1](=[O:4])([OH:3])[OH:2].[CH3:5][C:6](C)([C:8]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)([CH3:10])[CH3:9])C.Br>>[OH:17][C:14]1[CH:15]=[CH:16][C:11]([C:8]([CH3:9])([CH3:10])[CH2:6][CH2:5][P:1]([OH:3])(=[O:2])[OH:4])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 178442531HCID 178442531, compound

Product 1

HCID 54558383HCID 54558383, compound

Procedure

3.0 Parts of dimethyl-3-(4-hydroxyphenyl)-3-methyl-butane phosphonate from Example 23a and 30 parts of 48% hydrobromic acid were heated on a steam--bath for 1 hour and the volatiles then removed at 80° C. under reduced pressure. Crystallisation of the residual solid from water gave 3-(4-hydroxyphenyl)-3-methyl-butane phosphonic acid m.p. 192°-5° C. with the following percentage composition by weight.

Workup

  1. customthe volatiles then removed at 80° C. under reduced pressure
  2. customCrystallisation of the residual solid from water

Sources & evidence

ORD record
ord-f7e49e93f7e94ee184b5762a19661e5c
Source dataset
uspto-grants-1990_02
Patent number
US04904815

Reaction notes

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