Bromide ion → Tert-butyl 3-(5-methylpyridin-2-yl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzoate
Reaction equation
[Br-:25].[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([C:15]([C:16]([F:17])([F:18])[F:19])([C:20]([F:21])([F:22])[F:23])[OH:24])[cH:14]1.[CH3:26][c:27]1[cH:28][cH:29][c:30]([Zn+:33])[n:31][cH:32]1.[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[Zn:40]>>[c:2]1(-[c:30]2[cH:29][cH:28][c:27]([CH3:26])[cH:32][n:31]2)[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([C:15]([C:16]([F:17])([F:18])[F:19])([C:20]([F:21])([F:22])[F:23])[OH:24])[cH:14]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9b69c71b69e945699d929e5d1e81420b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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