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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1201300Generated: November 1, 2026

Bromide ion → Tert-butyl 3-(5-methylpyridin-2-yl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzoate

https://huagongshe.com/reaction/1201300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromide ionHCID 259—
ReactantZincHCID 23994—
Reactant1,4-DioxaneHCID 31275—
ReactantTert-butyl 3-bromo-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzoateHCID 86646752—
ReactantHCID 178427807HCID 178427807—
ProductTert-butyl 3-(5-methylpyridin-2-yl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzoateHCID 86646754—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-9b69c71b69e945699d929e5d1e81420b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)