Dichloromethane → ethyl 2-(1-(4-cyanonaphthalen-1-yl)-1H-imidazol-2-ylthio)-2,2-difluoroacetate

HRID 1201486Notes

Reaction equation

HRID 1201486 reaction equation
[Br:8][C:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])([F:15])[F:16].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:35][CH2:36][Cl:37].[SH:17][c:18]1[n:19](-[c:23]2[cH:24][cH:25][c:26]([C:33]#[N:34])[c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]23)[cH:20][cH:21][n:22]1>>[C:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])([F:15])([F:16])[S:17][c:18]1[n:19](-[c:23]2[cH:24][cH:25][c:26]([C:33]#[N:34])[c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]23)[cH:20][cH:21][n:22]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 69585Ethyl bromodifluoroacetateHCID 178510004HCID 178510004, compound

Product 1

HCID 59225900ethyl 2-(1-(4-cyanonaphthalen-1-yl)-1H-imidazol-2-ylthio)-2,2-difluoroacetate

Sources & evidence

ORD record
ord-67f326325a88483682bdfc94d89de845
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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