Dichloromethane → Trifluoroacetic acid

HRID 1201668Notes

Reaction equation

HRID 1201668 reaction equation
[C:1]([O:2][C:3](=[O:4])[n:8]1[c:9](-[c:17]2[c:18]([O:29][CH3:30])[n:19][n:20][c:21](-[c:23]3[cH:24][cH:25][n:26][cH:27][cH:28]3)[cH:22]2)[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12)([CH3:5])([CH3:6])[CH3:7].[Cl:38][CH2:39][Cl:40].[F:31][C:32]([C:33](=[O:34])[OH:35])([F:36])[F:37]>>[F:31][C:32]([C:33](=[O:34])[OH:35])([F:36])[F:37].[nH:8]1[c:9](-[c:17]2[c:18]([O:29][CH3:30])[n:19][n:20][c:21](-[c:23]3[cH:24][cH:25][n:26][cH:27][cH:28]3)[cH:22]2)[cH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 671488572-(3-Methoxy-6-pyridin-4-yl-pyridazin-4-yl)-indole-1-carboxylic acid tert-butyl ester

Product 2

HCID 6422Trifluoroacetic acidHCID 230924542-(3-methoxy-6-pyridin-4-ylpyridazin-4-yl)-1H-indole

Sources & evidence

ORD record
ord-b07523e5cae140fc81b00fb9978188c8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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