Hydrochloric Acid → N-[5-(2-Cyclopropyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-acetamide

HRID 1202083Notes

Reaction equation

HRID 1202083 reaction equation
[CH3:1][c:2]1[n:3][c:4]([NH:19][C:20]([CH3:21])=[O:22])[s:5][c:6]1-[c:7]1[n:8][c:9]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[n:10][cH:11][cH:12]1.[CH:24]1([C:27]([NH2:28])=[NH:29])[CH2:25][CH2:26]1.[ClH:23]>>[CH3:1][c:2]1[n:3][c:4]([NH:19][C:20]([CH3:21])=[O:22])[s:5][c:6]1-[c:7]1[n:8][c:9]([CH:24]2[CH2:25][CH2:26]2)[n:10][cH:11][cH:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 431751CyclopropanecarboximidamideHCID 86610334N-[4-Methyl-5-(2-morpholin-4-yl-pyrimidin-4-yl)-thiazol-2-yl]-acetamide

Product 1

HCID 11231150N-[5-(2-Cyclopropyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-acetamide

Sources & evidence

ORD record
ord-f0b18232e5af4e3c8e880c75824a85e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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