Tetrahydrofuran → N-(2-tert-butoxyethoxy)-6-(2-chloro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

HRID 1202187Notes

Reaction equation

HRID 1202187 reaction equation
[C:29]([CH3:30])([CH3:31])([CH3:32])[O:33][CH2:34][CH2:35][O:36][NH2:37].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[O:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1>>[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[NH:37][O:36][CH2:35][CH2:34][O:33][C:29]([CH3:30])([CH3:31])[CH3:32])[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 25108891Phenyl 6-(2-chloro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylateHCID 46856370O-(2-tert-butoxyethyl)hydroxylamine

Product 1

HCID 25108892N-(2-tert-butoxyethoxy)-6-(2-chloro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

Sources & evidence

ORD record
ord-4c8afc8847dd4afeb93c1f7c6a14d9aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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