Potassium Cation → 4-Fluoro-1-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:9]2([c:20]3[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[n:23][cH:24][cH:25]3)[N:10]=[C:11]([NH2:19])[c:12]3[c:13]([F:18])[cH:14][cH:15][cH:16][c:17]32)[cH:5][cH:6][c:7]1[F:8].[C:39](=[O:40])([O-:41])[O-:42].[K+:43].[K+:44].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[n:30]1[cH:31][n:32][cH:33][c:34]([B:36]([OH:37])[OH:38])[cH:35]1>>[c:2]1(-[c:34]2[cH:33][n:32][cH:31][n:30][cH:35]2)[cH:3][c:4]([C:9]2([c:20]3[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[n:23][cH:24][cH:25]3)[N:10]=[C:11]([NH2:19])[c:12]3[c:13]([F:18])[cH:14][cH:15][cH:16][c:17]32)[cH:5][cH:6][c:7]1[F:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b8fa5984273c42b6988b9a2d641ab553
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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