Acetate → 3-(4-Tert-butylphenyl)-5,5-dimethyl-1-[(2-{[6-(pyrrolidin-1-yl-methyl)pyridin-3-yl]amino}pyridin-4-yl)methyl]imidazolidine-2,4-dione

HRID 1202971Notes

Reaction equation

HRID 1202971 reaction equation
[Br:28][c:29]1[cH:30][cH:31][c:32]([CH2:35][N:36]2[CH2:37][CH2:38][CH2:39][CH2:40]2)[n:33][cH:34]1.[C:100]([O-:101])(=[O:102])[CH3:103].[C:83](=[O:84])([O-:85])[O-:86].[C:95]([O-:96])(=[O:97])[CH3:98].[CH3:41][C:42]1([CH3:43])[c:44]2[cH:45][cH:46][cH:47][c:48]([P:49]([c:50]3[cH:51][cH:52][cH:53][cH:54][cH:55]3)[c:56]3[cH:57][cH:58][cH:59][cH:60][cH:61]3)[c:62]2[O:63][c:64]2[c:65]1[cH:66][cH:67][cH:68][c:69]2[P:70]([c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1)[c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[Cs+:87].[Cs+:88].[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[C:10](=[O:27])[N:11]([c:17]3[cH:18][cH:19][c:20]([C:23]([CH3:24])([CH3:25])[CH3:26])[cH:21][cH:22]3)[C:12](=[O:16])[C:13]2([CH3:14])[CH3:15])[cH:7]1.[O:89]1[CH2:90][CH2:91][O:92][CH2:93][CH2:94]1.[Pd+2:99]>>[NH:1]([c:2]1[n:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[C:10](=[O:27])[N:11]([c:17]3[cH:18][cH:19][c:20]([C:23]([CH3:24])([CH3:25])[CH3:26])[cH:21][cH:22]3)[C:12](=[O:16])[C:13]2([CH3:14])[CH3:15])[cH:7]1)[c:29]1[cH:30][cH:31][c:32]([CH2:35][N:36]2[CH2:37][CH2:38][CH2:39][CH2:40]2)[n:33][cH:34]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 230909345-Bromo-2-(pyrrolidin-1-ylmethyl)pyridineHCID 576260021-[(2-Aminopyridin-4-yl)methyl]-3-(4-tert-butylphenyl)-5,5-dimethylimidazolidine-2,4-dione

Product 1

HCID 576260073-(4-Tert-butylphenyl)-5,5-dimethyl-1-[(2-{[6-(pyrrolidin-1-yl-methyl)pyridin-3-yl]amino}pyridin-4-yl)methyl]imidazolidine-2,4-dione

Sources & evidence

ORD record
ord-6ead89d2663b44359d0cba9cd1a9947d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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