Acetic Acid → 4-Bromo-3-methoxyphenol

HRID 1204272Notes

Reaction equation

HRID 1204272 reaction equation
[Br:1][c:2]1[c:3]([OH:9])[cH:4][c:5]([OH:6])[cH:7][cH:8]1.[C:10](=[O:11])([O-:12])[O-:13].[C:35]([OH:36])(=[O:37])[CH3:38].[CH3:27][I:28].[CH3:31][C:32](=[O:33])[CH3:34].[K+:14].[K+:15].[K+:30].[OH-:29].[c:16]1([CH3:17])[cH:18][cH:19][c:20]([S:21]([Cl:22])(=[O:23])=[O:24])[cH:25][cH:26]1>>[Br:1][c:2]1[c:3]([O:9][CH3:10])[cH:4][c:5]([OH:6])[cH:7][cH:8]1

Participants

9

Reactant 8

HCID 176Acetic AcidHCID 180AcetoneHCID 813Potassium Cation3×HCID 961HydroxideHCID 6328Methyl iodideHCID 73974-Toluenesulfonyl chlorideHCID 19660Carbonate IonHCID 811054-Bromoresorcinol

Product 1

HCID 3479554-Bromo-3-methoxyphenol

Sources & evidence

ORD record
ord-a4f91f55eecc42c5a36c94c7dff3264b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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