4-(Trifluoromethyl)benzylamine → N-isoquinolin-8-yl-N'-[4-(trifluoromethyl)benzyl]urea
Reaction equation
[CH2:30]1[CH2:31][CH2:32][C:33]2=[N:38][CH2:37][CH2:36][CH2:35][N:34]2[CH2:39][CH2:40]1.[Cl:13][C:14]([C:15](=[O:16])[NH:17][c:18]1[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][n:25][cH:26][c:27]12)([Cl:28])[Cl:29].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][NH2:8])[cH:9][cH:10]1)([F:11])[F:12]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:15](=[O:16])[NH:17][c:18]2[cH:19][cH:20][cH:21][c:22]3[cH:23][cH:24][n:25][cH:26][c:27]23)[cH:9][cH:10]1)([F:11])[F:12]Participants
4
Sources & evidence
- ORD record
- ord-1dab556677484a4ca21610913628901e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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