Hydrochloric Acid → 4-chloro-N-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-6-methylpyrimidin-2-amine

HRID 1204358Notes

Reaction equation

HRID 1204358 reaction equation
[CH3:21][c:22]1[cH:23][c:24]([Cl:25])[n:26][c:27]([NH2:28])[n:29]1.[Cl:2][c:3]1[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[c:9]([CH2:19][Cl:20])[c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2.[ClH:1]>>[Cl:2][c:3]1[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[c:9]([CH2:19][NH:28][c:27]1[n:26][c:24]([Cl:25])[cH:23][c:22]([CH3:21])[n:29]1)[c:10](-[c:12]1[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]1)[n:11]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 218102-Amino-4-chloro-6-methylpyrimidineHCID 583369006-Chloro-3-(chloromethyl)-2-(4-fluorophenyl)imidazo[1,2-a]pyridine

Product 1

HCID 866551224-chloro-N-((6-chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)-6-methylpyrimidin-2-amine

Sources & evidence

ORD record
ord-9226ba4b901846f7ad093788f7630b1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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