Dimethyl Sulfoxide → N-(4-Pentafluoroethyl-phenyl)-2-[(pyrimidin-4-ylmethyl)-amino]-nicotinamide
Reaction equation
[BH4-:43].[CH3:24][c:25]1[cH:26][cH:27][c:28]([S:29]([OH:30])(=[O:31])=[O:32])[cH:33][cH:34]1.[CH3:45][S:46]([CH3:47])=[O:48].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:13]([C:14]([F:15])([F:16])[F:17])([F:18])[F:19])[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1.[Na+:44].[n:35]1[cH:36][n:37][c:38]([CH:41]=[O:42])[cH:39][cH:40]1>>[NH:1]([c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][cH:9][c:10]([C:13]([C:14]([F:15])([F:16])[F:17])([F:18])[F:19])[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1)[CH2:41][c:38]1[n:37][cH:36][n:35][cH:40][cH:39]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f34f66e17c1441568b01958174817648
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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