2,2,2-Trifluoroethanol → 2-Amino-1-(4-hydroxy-4-phenylpiperidin-1-yl)-3,3-dimethylbutan-1-one

HRID 1204523Notes

Reaction equation

HRID 1204523 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([C:9]([CH3:10])([CH3:11])[CH3:12])[C:13](=[O:14])[N:15]1[CH2:16][CH2:17][C:18]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([OH:27])[CH2:19][CH2:20]1)([CH3:5])([CH3:6])[CH3:28].[OH:29][CH2:30][C:31]([F:32])([F:33])[F:34]>>[NH2:7][CH:8]([C:9]([CH3:10])([CH3:11])[CH3:12])[C:13](=[O:14])[N:15]1[CH2:16][CH2:17][C:18]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([OH:27])[CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 77276619tert-butyl N-[1-(4-hydroxy-4-phenylpiperidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]carbamate

Product 1

HCID 673862812-Amino-1-(4-hydroxy-4-phenylpiperidin-1-yl)-3,3-dimethylbutan-1-one

Sources & evidence

ORD record
ord-d2b91610e64f4255ae800295619be44d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…