Methanol → Methyl 6-((4-bromo-2-chlorophenyl)amino)-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

HRID 1204635Notes

Reaction equation

HRID 1204635 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][nH:11]2)[c:12]([F:22])[c:13]1[NH:14][c:15]1[c:16]([Cl:21])[cH:17][cH:18][cH:19][cH:20]1.[CH3:36][OH:37].[O:23]=[C:24]1[N:25]([Br:30])[C:26](=[O:27])[CH2:28][CH2:29]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][nH:11]2)[c:12]([F:22])[c:13]1[NH:14][c:15]1[c:16]([Cl:21])[cH:17][c:18]([Br:30])[cH:19][cH:20]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 67184N-bromobutanimideHCID 668977516-(2-Chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carboxylic acid methyl ester

Product 1

HCID 11749905Methyl 6-((4-bromo-2-chlorophenyl)amino)-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

Sources & evidence

ORD record
ord-3bd549b9347b44afb152c3e3e96fff51
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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