Benzene → 5,6,7,8-Tetrahydroquinoline-8-carbothioamide

HRID 1204678Notes

Reaction equation

HRID 1204678 reaction equation
[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:29][Si:30]([CH3:31])([CH3:32])[N:33]=[C:34]=[S:35].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[ClH:36].[OH2:43].[cH:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[n:19]1[cH:20][cH:21][cH:22][c:23]2[c:28]1[CH2:27][CH2:26][CH2:25][CH2:24]2>>[n:19]1[cH:20][cH:21][cH:22][c:23]2[c:28]1[CH:27]([C:34]([NH2:33])=[S:35])[CH2:26][CH2:25][CH2:24]2

Participants

9

Reactant 8

HCID 241BenzeneHCID 313Hydrochloric AcidHCID 962WaterHCID 7912DiisopropylamineHCID 8058HexaneHCID 663355,6,7,8-TetrahydroquinolineHCID 75297IsothiocyanatotrimethylsilaneHCID 178418339Butyllithium

Product 1

HCID 122782125,6,7,8-Tetrahydroquinoline-8-carbothioamide

Sources & evidence

ORD record
ord-319886b4d8b6485da46893b80f80f6d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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