Quinoline → 1-[4-(7-Trifluoromethyl-benzo[b]thiophen-3-yl)-piperidin-1-yl]-ethanone
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([c:10]2[c:11]3[c:12]([s:13][c:14]2[C:15]([OH:16])=[O:17])[c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]3)[CH2:8][CH2:9]1.[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[cH:26]1[cH:27][c:28]2[c:29]([n:30][cH:31][cH:32][cH:33]2)[cH:34][cH:35]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([c:10]2[c:11]3[c:12]([s:13][cH:14]2)[c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]3)[CH2:8][CH2:9]1Participants
4
Sources & evidence
- ORD record
- ord-5ae1b9445b534d49982a5dc97d5e43eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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