Acetone → 8-Chloro-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one
Reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[S:10][c:11]3[c:12]([cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[NH:13][C:14](=[O:17])[CH:15]2[OH:16])[cH:7][cH:8]1.[CH3:24][N:25]([CH2:26][CH2:27][Cl:28])[CH3:29].[CH3:36][C:37](=[O:38])[CH3:39].[ClH:23].[K+:34].[K+:35]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[S:10][c:11]3[c:12]([cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[N:13]([CH2:27][CH2:26][N:25]([CH3:24])[CH3:29])[C:14](=[O:17])[CH:15]2[OH:16])[cH:7][cH:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-34e7cb6954bb4eab9f178d87820a5d8d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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