Acetone → Hydrochloric Acid

HRID 1205080Notes

Reaction equation

HRID 1205080 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([F:17])[cH:14][c:15]2[CH2:16]1.[CH3:20][C:21](=[O:22])[CH3:23].[CH3:25][CH2:26][OH:27].[ClH:24].[H:18][H:19].[OH-:28].[OH-:30].[Pd+2:29]>>[ClH:24].[NH:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([F:17])[cH:14][c:15]2[CH2:16]1

Participants

9

Reactant 7

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 179862982-Benzyl-5-fluoroisoindolineHCID 178418361HCID 178418361, compound

Product 2

HCID 313Hydrochloric AcidHCID 147958695-Fluoro-2,3-dihydro-1H-isoindole

Sources & evidence

ORD record
ord-c917eda7948647d2b9a4fa1acf0afdf8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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