HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene → 8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]decane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene | HCID 15232682 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]decane | HCID 12834404 | — |
Reaction Steps
8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene is hydrogenated using Pd/C with hydrogen. After filtering-off of the catalyst over celite and evaporating-off of the solvent, 8-(4-fluorophenyl)-1,4-dioxaspiro[4.5]decane is obtained in a quantitative yield: tR 3.65 min (LC-1); ESI-MS(+): m/z 237.26 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07727979B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d3ec7ce35c5743429efed8cc6b073b42 |
| Source note | uspto-grants-2010_06 |