Sodium ion → 1-(t-Butoxycarbonyl)-3-[2-(2-fluoro-5-bromobenzyloxy)ethyl]piperidine

HRID 1205406Notes

Reaction equation

HRID 1205406 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][CH2:15][Br:16])[CH2:11][CH2:12][CH2:13]1.[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[F:19][c:20]1[c:21]([CH2:22][OH:23])[cH:24][c:25]([Br:28])[cH:26][cH:27]1.[H-:29].[I-:18].[Na+:17].[Na+:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][CH2:15][O:23][CH2:22][c:21]2[c:20]([F:19])[cH:27][cH:26][c:25]([Br:28])[cH:24]2)[CH2:11][CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 30165Iodide IonHCID 166653HydrideHCID 2773352(5-Bromo-2-fluorophenyl)methanolHCID 21188829tert-Butyl 3-(2-bromoethyl)piperidine-1-carboxylate

Product 1

HCID 211961361-(t-Butoxycarbonyl)-3-[2-(2-fluoro-5-bromobenzyloxy)ethyl]piperidine

Sources & evidence

ORD record
ord-7b4f7f143e5c4e498287f9555c0e3028
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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