Potassium Cation → 1-[3-[4-(1,1-Dimethylethyl)phenoxy]propyl]-alpha,alpha-bis(4-fluorophenyl)-4-piperidinemethanol
Reaction equation
[CH:40]([OH:41])([CH3:42])[CH3:43].[Cl:23][CH2:24][CH2:25][CH2:26][O:27][c:28]1[cH:29][cH:30][c:31]([C:34]([CH3:35])([CH3:36])[CH3:37])[cH:32][cH:33]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:6][cH:7]1.[I-:39].[K+:38]>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([OH:9])([CH:10]2[CH2:11][CH2:12][N:13]([CH2:24][CH2:25][CH2:26][O:27][c:28]3[cH:29][cH:30][c:31]([C:34]([CH3:35])([CH3:36])[CH3:37])[cH:32][cH:33]3)[CH2:14][CH2:15]2)[c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-8462562fae104923b7258ce6b1bdb830
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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