Dichloromethane → 9'-(Trifluoromethyl)-spiro[piperidine-4,6'-pyrido[2,3-b]pyrrolo[1,2-d][1,4]oxazine]
Reaction equation
[Cl:37][CH2:38][Cl:39].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[n:7]1-[c:8]1[c:9]([n:24][cH:25][cH:26][cH:27]1)[O:10][C:11]21[CH2:12][CH2:13][N:14]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:15][CH2:16]1)([F:28])[F:29].[F:30][C:31]([F:32])([F:33])[C:34]([OH:35])=[O:36]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[n:7]1-[c:8]1[c:9]([n:24][cH:25][cH:26][cH:27]1)[O:10][C:11]21[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1)([F:28])[F:29]Participants
4
Sources & evidence
- ORD record
- ord-d5b23ed7b0904bf3a662a48eb0018de5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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