Tetrahydrofuran → 2-(1-(bis(tert-butoxycarbonyl)amino)isoquinolin-6-ylamino)-2-(4-(2-hydroxypropyl)phenyl)-N-(3-nitrobenzyl)acetamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([c:9]1[n:10][cH:11][cH:12][c:13]2[cH:14][c:15]([NH:19][CH:20]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([N+:31](=[O:32])[O-:33])[cH:28][cH:29][cH:30]3)[c:34]3[cH:35][cH:36][c:37]([CH2:40][CH:41]([CH3:42])[O:43][Si:44]([C:45]([CH3:46])([CH3:47])[CH3:48])([CH3:49])[CH3:50])[cH:38][cH:39]3)[cH:16][cH:17][c:18]12)[C:51](=[O:52])[O:53][C:54]([CH3:55])([CH3:56])[CH3:57].[CH2:59]([N+:60]([CH2:61][CH2:62][CH2:63][CH3:64])([CH2:65][CH2:66][CH2:67][CH3:68])[CH2:69][CH2:70][CH2:71][CH3:72])[CH2:73][CH2:74][CH3:75].[CH2:76]1[O:77][CH2:78][CH2:79][CH2:80]1.[F-:58]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([c:9]1[n:10][cH:11][cH:12][c:13]2[cH:14][c:15]([NH:19][CH:20]([C:21](=[O:22])[NH:23][CH2:24][c:25]3[cH:26][c:27]([N+:31](=[O:32])[O-:33])[cH:28][cH:29][cH:30]3)[c:34]3[cH:35][cH:36][c:37]([CH2:40][CH:41]([CH3:42])[OH:43])[cH:38][cH:39]3)[cH:16][cH:17][c:18]12)[C:51](=[O:52])[O:53][C:54]([CH3:55])([CH3:56])[CH3:57]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-06c0f9cde2d049f99fe7a1302e7cf918
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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