Hydrochloric Acid → 4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline

HRID 1205985Notes

Reaction equation

HRID 1205985 reaction equation
[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([N+:24]([O-:25])=[O:26])[cH:22][cH:23]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][c:13]2[F:14])[nH:15][cH:16][cH:17]3)[cH:7]1.[CH3:29][CH2:30][OH:31].[ClH:28].[Sn:27]>>[CH2:1]([CH3:2])[n:3]1[n:4][c:5](-[c:18]2[cH:19][cH:20][c:21]([NH2:24])[cH:22][cH:23]2)[c:6](-[c:8]2[c:9]3[c:10]([n:11][cH:12][c:13]2[F:14])[nH:15][cH:16][cH:17]3)[cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 5352426Tin atomHCID 689982384-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-5-fluoro-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 690026924-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline

Sources & evidence

ORD record
ord-9352f851943142bfb92a34e338d826eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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