Dichloromethane → tert-Butyl 2-(bromomethyl)morpholine-4-carboxylate

HRID 1206083Notes

Reaction equation

HRID 1206083 reaction equation
[Br:16][C:17]([Br:18])([Br:19])[Br:20].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][OH:15])[O:11][CH2:12][CH2:13]1.[Cl:40][CH2:41][Cl:42].[c:21]1([P:22]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:14][Br:16])[O:11][CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 5201202tert-Butyl 2-(hydroxymethyl)morpholine-4-carboxylate

Product 1

HCID 57418765tert-Butyl 2-(bromomethyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-3567b9e979ad4052bbb31d7dbebd37af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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