Dimethylformamide → tert-butyl N-[4-(4-bromopyrazol-1-yl)-1-(4-chlorophenyl)butan-2-yl]carbamate

HRID 1206099Notes

Reaction equation

HRID 1206099 reaction equation
[Br:1][c:2]1[cH:3][n:4][nH:5][cH:6]1.[C:7](=[O:8])([O-:9])[O-:10].[CH3:13][S:14]([O:15][CH2:18][CH2:19][CH:20]([CH2:21][c:22]1[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]1)[NH:29][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])(=[O:16])=[O:17].[Cl:42][CH2:43][Cl:44].[Cs+:11].[Cs+:12].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[Br:1][c:2]1[cH:3][n:4][n:5]([CH2:18][CH2:19][CH:20]([CH2:21][c:22]2[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[NH:29][C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[cH:6]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 163754-BromopyrazoleHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 76673410[4-(4-Chlorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butyl] methanesulfonate

Product 1

HCID 67062710tert-butyl N-[4-(4-bromopyrazol-1-yl)-1-(4-chlorophenyl)butan-2-yl]carbamate

Sources & evidence

ORD record
ord-7c95f93122b24ff0b5feb6ff66d52145
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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