Water → N-(2-Chloro-benzyl)-2-(3-fluoro-phenoxy)-nicotinamide
Reaction equation
[CH2:36]([Cl:37])[Cl:38].[Cl:18][C:19]([O:20][CH2:21][CH:22]([CH3:23])[CH3:24])=[O:25].[Cl:26][c:27]1[c:28]([CH2:29][NH2:30])[cH:31][cH:32][cH:33][cH:34]1.[F:1][c:2]1[cH:3][c:4]([O:5][c:6]2[c:7]([C:8](=[O:9])[OH:10])[cH:11][cH:12][cH:13][n:14]2)[cH:15][cH:16][cH:17]1.[OH2:35]>>[F:1][c:2]1[cH:3][c:4]([O:5][c:6]2[c:7]([C:8](=[O:10])[NH:30][CH2:29][c:28]3[c:27]([Cl:26])[cH:34][cH:33][cH:32][cH:31]3)[cH:11][cH:12][cH:13][n:14]2)[cH:15][cH:16][cH:17]1Participants
6
Sources & evidence
- ORD record
- ord-d3a5de8c5e8b4ac5b37750f2879582a5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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